Louis-Dreyfus has received seven Emmy Awards, with a total of 21 nominations throughout her career.
Louis-Dreyfus broke into comedy as a performer in The Practical Theatre Company in Chicago, Illinois, which led to her casting in the sketch show, Saturday Night Live, from 1982 to 1985.
She is known for her work in television comedy, including Saturday Night Live 1982—85 , Seinfeld 1989—98 , The New Adventures of Old Christine 2006—10 , and Veep 2012—present.
In 2016, Time named Louis-Dreyfus one of the 100 most influential people in the world on the annual Time 100 list.
Louis-Dreyfus received a star on the Hollywood Walk of Fame in 2010, and was inducted into the Television Academy Hall of Fame in 2014.